La 8 Loetse, 2025, InnoCare Pharma e phatlalalitse hore HIBRUKA (orelabrutinib) e amohetsoe ke Bolaodi ba Saense ea Bophelo (HSA) ba Singapore bakeng sa kalafo ea bakuli ba baholo ba nang le lymphoma ea marginal zone e khutlileng hape kapa e sa arabeleng (R/R MZL).
Hona jwale, ho ntse ho na le diteko tse ngata tsa bongaka tsa mahlale a matjha a ho lwantsha kankere Chaena a batlang bakudi. Dipuisano mabapi le meriana le mahlale a matjha, o ka ikopanya le Lefapha la Matjhaba la Sepetlele sa Oncology sa Beijing Region South.
Nomoro ea mohala: 4008803716
Nomoro ea WeChat: 17801183037
Email：myimmnet@163.com
Marginal zone lymphoma (MZL) ke lymphoma ea B-cell e seng Hodgkin's (NHL) e sa sebetseng hantle e amang bakuli ba lilemo tse mahareng le ba hōlileng. Palo ea selemo le selemo ea MZL e ntse e eketseha lefatšeng ka bophara. Kamora kalafo ea pele, bakuli ba nang le R/R MZL ha ba na mekhoa e sebetsang ea kalafo.
Ka Mmesa 2025, orelabrutinib e ile ea amoheloa Chaena bakeng sa kalafo ea pele ea bakuli ba nang le chronic lymphocytic leukemia (CLL) / small lymphocytic lymphoma (SLL). Orelabrutinib le eona e amohetsoe bakeng sa kalafo ea matšoao a mang a mararo Chaena, ho kenyeletsoa le repeat and refractory (R/R) CLL/SLL, r/r mantle cell lymphoma (R/R MCL) le r/r marginal zone lymphoma (R/R MZL), tseo kaofela li koahetsoeng Lethathamong la Meriana la Naha la Puseletso ea Chaena.
Katleho, Polokeho, le Bokgoni ba Orelabrutinib Plus Obinutuzumab ho Systemic Treatment-Naive Marginal Zone Lymphoma: Phuputso ya Prospective Cohort e bontshitse hore Ho pholletsa le thuto yohle le nakong ya kalafo ya induction, sekgahla sa karabelo ya kakaretso (ORR) ke 100%. Bakuli ba bararo ba nang le karabelo e sa fellang (PR) kamora kalafo ya induction ba fihletse karabelo e felletseng (CR) nakong ya tlhokomelo.
Liteko tsa ADCC li bontšitse hore orelabrutinib hammoho le mokhoa oa obinutuzumab li bakile karabelo e sebetsang ka ho fetisisa ea ADCC meleng ea lisele tsa TMD-8 le REC-1.
Hona jwale, ho ntse ho na le diteko tse ngata tsa bongaka tsa mahlale a matjha a ho lwantsha kankere Chaena a batlang bakudi. Dipuisano mabapi le meriana le mahlale a matjha, o ka ikopanya le Lefapha la Matjhaba la Sepetlele sa Oncology sa Beijing Region South.
Nomoro ea mohala: 4008803716
Nomoro ea WeChat: 17801183037
Email：myimmnet@163.com
Nako ea poso: Loetse-09-2025